EPOS

European Paediatric Ophthalmological Society

Abstract Preview

32 Persistent fetal vasculature syndrome in infants

Saidacheva, E.
Dept. of Pediatric Ophthalmology, Children's Hospital N1, St.Petersburg

Purpose:. To review our experience with patients suffering from persistent fetal vasculature (PFV) syndrome based on a retardation of reverse development of fetal intraocular vessels, particularly, hyaloid arteries.

Methods:. Between February 1999 and May 2000 six children with leukoria from various regions of the Russian Federation were admitted to our clinic (Eye Research Institute, Ufa, Russia) for making their diagnosis more precise. The mean age of infants at diagnosis was about 8 months.

Results:. At complete ophthalmic examination under general anesthesia including B-scanning and computer tomography, various symptoms of PFV syndrome were found in all patients (12 eyes); cataract (9 eyes) including the Mittendorf dot (4 eyes) and total tens opacification (5 eyes): vitreous fibrosis (8 eyes), retinal detachment (5 eyes). Rough changes in the vitreous body in the absolute majority of eyes examined (5 out of 6) were combined with retinal detachment apparently developing as a result of fibrovascular tissue traction. The so called PFV posterior reading with the process progression and development of lenticular opacification; secondary glaucoma and retinal detachment caused by the retrolental tissue shrinkage with anterior shift of the lenti-iridal diaphragm was observed in one patient (2. eyes). Individual components of the syndrome associated with others manifested in all cases. Marked neurologic disorders with prevalence of hydrocephale syndrome confirmed by neurosonography were noted in all infants seen.

Conclusion:. Infants with various forms of leukoria need profound examination on the pediatric ophthalmology service for early diagnosis of PFV-syndrome and devising treatment tactics.